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INHIBITION

         Chemicals which decrease the rate of enzyme catalyzed reactions are called inhibition.

               There are 3 types of inhibition
               
                  1. Competitive inhibition
                  2. Non competitive inhibition
                  3. End product inhibition


                                                1. Competitive inhibition 

                      competitive inhibition are some what similar to the specific substrate  of the enzyme and they can fit into the active site of enzyme.
                       competition occurs between the specific substrate molecule and inhibitor molecule to occupy active sites.

                                             2. Non competitive inhibition 

                     Non competitive inhibitors do not combine with the active site of the enzyme instead they fit into ALLOSTERIC   SITE. Therefore substrate unable to combine with enzyme . As the enzyme substrate formation is affected reaction rate decreases . This inhibition cam be reversible or irreversible.


                                            3. End product inhibition 

                     When the end product of a series of reaction causes and inhibition over one or more enzyme of the path. It referred as end product inhibition. 
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